Host immune system strikes back
نویسندگان
چکیده
منابع مشابه
Host immune system strikes back
Autophagy-mediated major histocompatibility complex (MHC) class I presentation can follow either the conventional MHC class I pathway or a recently described vacuolar pathway. In the vacuolar pathway, protein degradation is effected by lysosomal proteases, peptide exchange takes place with recirculating MHC complexes and the newly formed peptide-MHC complexes reach the cell surface by the endoc...
متن کاملThe Immune System Strikes Back: Cellular Immune Responses against Indoleamine 2,3-dioxygenase
BACKGROUND The enzyme indoleamine 2,3-dioxygenase (IDO) exerts an well established immunosuppressive function in cancer. IDO is expressed within the tumor itself as well as in antigen-presenting cells in tumor-draining lymph nodes, where it promotes the establishment of peripheral immune tolerance to tumor antigens. In the present study, we tested the notion whether IDO itself may be subject to...
متن کاملThe Keloid Strikes Back
DESCRIPTION A 12-year-old African American woman presented to a plastic surgeon with a 1-year history of a slowly growing soft tissue mass behind her left ear. According to her, she had chicken pox and a residual pock mark behind that ear. As a result of irritation in that area from her glasses, she developed a cosmetically deforming keloid shown on the left. The keloid was subsequently excised...
متن کاملThe robber strikes back
We consider the new game of Cops and Attacking Robbers, which is identical to the usual Cops and Robbers game except that if the robber moves to a vertex containing a single cop, then that cop is removed from the game. We study the minimum number of cops needed to capture a robber on a graph G, written cc(G). We give bounds on cc(G) in terms of the cop number of G in the classes of bipartite gr...
متن کاملChange strikes back
European Journal of Information Systems (2007) 16, 1–2. doi:10.1057/palgrave.ejis.3000668 Predicting the effect of change can be difficult if not impossible. A year ago in the first editorial of Volume 15, I stated ‘because special issues are on the increase, this reduces the pool of papers available for general submission, y’ and ‘y dilution of the general stream of submissions with the remova...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Autophagy
سال: 2012
ISSN: 1554-8627,1554-8635
DOI: 10.4161/auto.21860